Module manager: Dr Joan Boyes
Email: j.m.boyes@leeds.ac.uk
Taught: Semesters 1 & 2 (Sep to Jun) View Timetable
Year running 2019/20
Successful completion of Year one of the above degree programmes
| BIOC1301 | Introductory Integrated Biochemistry: the Molecules and Proc |
| BIOC1302 | Introductory Biochemistry: Practical Skills |
| BIOC1303 | Introductory Biochemistry: Problem Solving and Data Handling |
This module is not approved as a discovery module
The module builds upon the introductory biochemistry of molecules, pathways and cells studied at level one.
On completion of this module, students will have developed knowledge and extended further their understanding along the following major themes:
1. Protein Structure and Function Theme (Semester one)
2. Genetic Engineering Theme (Semester one)
3. Cell Biology Theme (Semesters one)
4. Biological membranes Theme (Semester two)
5. Genes Theme (Semester two).
Semster 1:
Protein Structure and Function Theme:
- Ligand binding
- Structural biology techniques
a. mass spectometry
b. x-ray crystallography
c. electron microscopy
d. NMR
e. AFM
- Enzyme kinetics
- Protein folding
- Protein chaperones
- Antibody structure and function
- RNA biology
- Bioinformatics
- Bacterial infections.
Genetic Engineering Theme:
- Gene cloning
- DNA mutagenesis
- Recombinant protein expression systems
- RNA interference
- In vivo monitoring via GFP
- PCR and quantitative PCR
Cell Biology Theme:
Structure and function of individual organelles including:
a. the cytoskeleton
b. the nucleus
c. the endoplasmic reticulum
d. mitochondria
e. lysosymes
f. peroxisomes
g. ion channels
h. cell receptors
Cell biological techniques and high throughput technologies.
Properties of cell types including:
a. immune cells
b. endothelial cells
c. cancer cells
d. neuronal cells
Semester 2:
Membranes Theme:
a. Membranes assembly and biosynthesis
b. Photosynthesis
c. Mitochondria, electron transport and ATP synthesis
d. Transport and ion channels
e. Lipid signalling
f. Membrane signalling and second messengers
g. Plant signalling
h. Nuclear hormones.
Genes Theme:
Eukaryotic Gene expression including:
a. Epigenetics
b. Transcription factors and their modifications
c. Long range regulatory elements
The Cell cycle. Genetic diseases including:
a. Genome organisation
b. Linkage to disease markers
c. forensic analysis
d. molecular diagnosis
- V(D) J recombination
- Molecular biology of cancer.
| Delivery type | Number | Length hours | Student hours |
|---|---|---|---|
| Lecture | 120 | 1 | 120 |
| Private study hours | 480 | ||
| Total Contact hours | 120 | ||
| Total hours (100hr per 10 credits) | 600 | ||
Students should note that the following information is for guidance only. The actual time required for the various elements will vary between students.
- 2.5 hours of self-study per lecture (300 hours)
- 180 hours - examination and coursework preparation.
- Student attendance at lectures will be monitored in line with standard faculty practice.
- Completion of coursework assessment and exam.
- Engagement with VLE resources.
| Assessment type | Notes | % of formal assessment |
|---|---|---|
| In-course MCQ | Protein Structure & Function | 4 |
| In-course MCQ | Health & Disease: Cell Biology (1) | 4 |
| In-course MCQ | Health & Disease: Genes(2) | 4 |
| In-course MCQ | Membranes & signalling | 4 |
| In-course Assessment | Health & Disease: Cell Biology | 5 |
| In-course MCQ | Genetic Engineering | 4 |
| Total percentage (Assessment Coursework) | 25 | |
Students will need to engage with VLE resources.
| Exam type | Exam duration | % of formal assessment |
|---|---|---|
| Standard exam (closed essays, MCQs etc) | 2.0 Hrs Mins | 20 |
| Standard exam (closed essays, MCQs etc) | 2.0 Hrs Mins | 20 |
| Standard exam (closed essays, MCQs etc) | 3.0 Hrs Mins | 35 |
| Total percentage (Assessment Exams) | 75 | |
Paper 1 - week 12, MRQ and short question exam (2 hours) covering Semester 1 topics Paper 2: Semester 2 - combined MRQs and short answer questions - covering Semester 1 & 2 topics (2 hours). Paper 3: Semester 2 - Essay questions testing topics in semester 1 & 2 (3 hours).
The reading list is available from the Library website
Last updated: 14/08/2019
Errors, omissions, failed links etc should be notified to the Catalogue Team